The Familial or Hereditary Nephropathy (FN) is a juvenile-onset fatal kidney disease in English Cocker Spaniels.

 

The renal disease caused by FN invariably is progressive and ultimately fatal. Dogs with FN typically develop chronic renal failure between 6 month and 2 years of age, with eventual and sometimes rapid destruction of both kidneys. The first clinical signs are excessive water consumption, growth rate or loss in weight, reduced appetite, and vomiting.